I tried with
# pep8: disable=E223
As far as I know, you can't. You can disable errors or warnings user wide, or per project. See the documentation.
Instead, you can use the
# noqa comment at the end of a line, to skip that particular line (see patch 136). Of course, that would skip all PEP8 errors.
The main author argues against source file noise, so they suggested
# pep8 comments don't get included.